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pentobarbital will minimize the extent or effect of tacrolimus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.pentobarbital will reduce the level or effect of terbinafine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital decreases levels of toremifene by impacting hep